35789-58900*(678899+7890)

Let's break down the calculation step by step:

1. Calculate the inner parentheses first: 678899 + 7890 = 686789
2. Then, multiply the result by -58900: -58900 * 686789 = -40,473,721
3. Finally, subtract 35789 from the result: -40,473,721 - 35789 = -40,509,510

Therefore, the final answer is -40,509,510.