35789-58900*(678899+7890)

Let's simplify the expression step by step:

1. 35789 - 58900 * (678899 + 7890)
2. 35789 - 58900 * 686789
3. 35789 - 40457212100
4. -40457176311

Therefore, the result of the expression 35789 - 58900*(678899+7890) is -40,457,176,311.