2-6+45-24+37-146-2+43^4*1833

To calculate the expression:

2 - 6 + 45 - 24 + 37 - 146 - 2 + 43^4 * 1833

we follow the order of operations (PEMDAS):

1. First, calculate the exponents: 43^4 = 43 * 43 * 43 * 43 = 35,814,149

2. Then, perform multiplication: 35,814,149 * 1833 = 65,692,619,217

3. Finally, perform addition and subtraction: 2 - 6 + 45 - 24 + 37 - 146 - 2 + 65,692,619,217 = 65,692,611,123

Therefore, the result of the expression is 65,692,611,123.