190-7390*678

To calculate \( 190 - 7390 \times 678 \), we first perform the multiplication:

\[ 7390 \times 678 = 5,008,020 \]

Now we subtract this from 190:

\[ 190 - 5,008,020 = -5,007,830 \]

So, the final answer is:

\[ \boxed{-5,007,830} \]