33•17-21•19+2020:10+4157

Let's solve the expression step by step.

1. Calculate \(33 \times 17\): \[ 33 \times 17 = 561 \]

2. Calculate \(21 \times 19\): \[ 21 \times 19 = 399 \]

3. Calculate \(2020 \div 10\): \[ 2020 \div 10 = 202 \]

4. Now, substitute these values back into the expression: \[ 561 - 399 + 202 + 4157 \]

5. Perform the subtraction: \[ 561 - 399 = 162 \]

6. Now add \(202\): \[ 162 + 202 = 364 \]

7. Finally, add \(4157\): \[ 364 + 4157 = 4521 \]

So the final result is: \[ \boxed{4521} \]