-4,27+3,8-5,73-3,3

Let's calculate the expression step by step:

1. Start with -4.27.

2. Add 3.8: \(-4.27 + 3.8 = -0.47\).

3. Subtract 5.73: \(-0.47 - 5.73 = -6.20\).

4. Finally, subtract 3.3: \(-6.20 - 3.3 = -9.50\).

Therefore, the result of the expression \(-4.27 + 3.8 - 5.73 - 3.3\) is \(-9.50\).