250-250:(-65+15)*(-2)

To solve the expression \( 250 - 250 : (-65 + 15) \times (-2) \), we can break it down step by step:

1. Calculate \(-65 + 15\): \[ -65 + 15 = -50 \]

2. Now substitute this back into the expression: \[ 250 - 250 : (-50) \times (-2) \]

3. Now calculate \(-50 \times -2\): \[ -50 \times -2 = 100 \]

4. Substitute \(100\) into the expression: \[ 250 - 250 : 100 \]

5. Now the division \(250 : 100\) (which is the same as \(250 \div 100\)): \[ 250 \div 100 = 2.5 \]

6. Substitute back again: \[ 250 - 2.5 \]

7. Finally, calculate \(250 - 2.5\): \[ 250 - 2.5 = 247.5 \]

Thus, the final result is: \[ \boxed{247.5} \]