-1•2•4-4•-1-5•8

To evaluate the expression \(-1 \cdot 2 \cdot 4 - 4 \cdot -1 - 5 \cdot 8\), we will follow the order of operations:

1. Multiply the terms:

   • \(-1 \cdot 2 = -2\)
   • \(-2 \cdot 4 = -8\)
   • \(-4 \cdot -1 = 4\)
   • \(-5 \cdot 8 = -40\)

2. Substitute these results back into the expression:

   • \(-8 + 4 - 40\)

3. Combine the results:

   • \(-8 + 4 = -4\)
   • \(-4 - 40 = -44\)

The final result of the expression \(-1 \cdot 2 \cdot 4 - 4 \cdot -1 - 5 \cdot 8\) is \(-44\).