100*500+309-744*529

Let's calculate the expression step by step:

1. First, calculate the multiplication:

   • \( 100 \times 500 = 50000 \)
   • \( 744 \times 529 = 393936 \)

2. Now, substitute these values into the expression:

   • \( 50000 + 309 - 393936 \)

3. Next, perform the addition:

   • \( 50000 + 309 = 50309 \)

4. Finally, subtract:

   • \( 50309 - 393936 = -343627 \)

So, the result of the expression \( 100 \times 500 + 309 - 744 \times 529 \) is \(-343627\).