To simplify the expression \( a^6 \cdot a^{-10} \), you can use the property of exponents that states:
\[ a^m \cdot a^n = a^{m+n} \]
Applying this property here:
\[ a^6 \cdot a^{-10} = a^{6 + (-10)} = a^{-4} \]
So, the simplified form of the expression is:
\[ a^{-4} \]
If desired, you can also express this in a different form:
\[ a^{-4} = \frac{1}{a^4} \]
Thus, \( a^6 \cdot a^{-10} = a^{-4} = \frac{1}{a^4} \).