Let's solve the expression step by step.
The expression is:
\[ (8:8*16):2*1000*8 \]
Start with the innermost operation. According to the order of operations (parentheses, exponents, multiplication and division from left to right, addition and subtraction from left to right), we first deal with the division inside the parentheses:
\[ 8:8 = 1 \]
Now substitute back into the expression:
\[ (1*16):2*1000*8 \]
Now we can simplify:
\[ 1*16 = 16 \]
Substitute again:
\[ 16:2*1000*8 \]
Next, handle the division:
\[ 16:2 = 8 \]
Substitute back in:
\[ 8*1000*8 \]
Now perform the multiplication:
\[ 8*1000 = 8000 \]
Finally, multiply by 8:
\[ 8000*8 = 64000 \]
So, the result of the expression \( (8:8*16):2*1000*8 \) is \( \textbf{64000} \).