48х(1-5)

To solve \( 48 \times (1 - 5) \), first simplify the expression inside the parentheses:

\[ 1 - 5 = -4 \]

Now, substitute that back into the equation:

\[ 48 \times (-4) \]

Next, perform the multiplication:

\[ 48 \times (-4) = -192 \]

So, the final answer is:

\[ -192 \]