To simplify the expression \((3x^5 - 5y)(3x^5 + 5y)\), you can use the difference of squares formula, which states that \( (a - b)(a + b) = a^2 - b^2 \).
Here, let:
- \( a = 3x^5 \)
- \( b = 5y \)
Now, applying the difference of squares formula:
\[ (3x^5 - 5y)(3x^5 + 5y) = (3x^5)^2 - (5y)^2 \]
Calculating each square:
\[ (3x^5)^2 = 9x^{10} \] \[ (5y)^2 = 25y^2 \]
Putting it all together:
\[ (3x^5 - 5y)(3x^5 + 5y) = 9x^{10} - 25y^2 \]
So, the final simplified expression is:
\[ \boxed{9x^{10} - 25y^2} \]